Every NYC block is its own village, which is why it can be risky to slap a label of any kind on an entire neighborhood. AmNewYork tries it anyway in a recent round-up of slumber-friendly neighborhoods.
It turns out that the areas that quiet down most after dark--the Upper West and Upper East Sides, Tribeca, and Battery Park City--are also well-known magnets for families. (Of course, even if you have no kids yourself, you'll be up early too, what with the pitter patter of recharged little feet overhead.)
The loudest neighborhoods at night--East Village, Lower East Side, West Chelsea and the Meatpacking District--cater to the over-five-feet and ready to party demographic.
As one real estate broker says, "The East Village definitely takes the award for most bars per square block." Translation: "You could be up all night, since everyone else is."